“Knowledge of the relation of hormones to enzymes involved in calcification processes, the potential origin and appearance of like and mutant characters described in genetics, and the radioactive tracers of metabolic activity in dental tissues all point to the myopia of interest restricted to the local environment of the teeth.

“Accepting the challenge imposed by new knowledge does not mean that the chemico-parasitic theory in its entirety should be discarded. But there are facts that will not fit into it, and from knowledge now available there is reason to believe that these facts may be explained by a more comprehensive scheme of approach.”